Characteristic | n (%) | p-value | ||
TTR | miR-145# | miR-367# | ||
Sex | ||||
Male | 58 (82.9) | 0.02 | 0.535 | 0.545 |
Female | 12 (17.1) | |||
Age years | ||||
≤65 | 31 (44.3) | 0.965 | 0.050 | 0.655 |
>65 | 39 (55.7) | |||
Performance status | ||||
0 | 7 (10) | 0.861 | 0.5 | 0.277 |
1 | 63 (90) | |||
Stage | ||||
I | 44 (62.9) | 0.374 | 0.758 | 0.874 |
II | 12 (17.1) | |||
III | 14 (20) | |||
Histology | ||||
Adenocarcinoma | 36 (51.4) | 0.49 | 0.364¶ | 0.926¶ |
Squamous cell carcinoma | 28 (40) | |||
Others | 6 (8.6) | |||
Type of surgery | ||||
Lobectomy/bilobectomy | 59 (84.3) | 0.27 | ||
Pneumonectomy | 5 (7.1) | |||
Atypical resection | 6 (8.6) | |||
Smoking history | ||||
Current smoker | 22 (31.4) | 0.184 | 0.082 | 0.587 |
Former smoker | 40 (57.1) | |||
Never-smoker | 6 (8.6) | |||
Unknown | 2 (2.9) | |||
Adjuvant chemotherapy | ||||
Yes | 15 (21.4) | 0.774 | ||
No | 55 (78.6) | |||
Relapse | ||||
No | 47 (67.1) | |||
Yes | 23 (32.9) | |||
p53 mutated | ||||
Yes | 13 (20.3) | 0.002 | 0.009 | 0.555 |
No | 51 (79.7) |
TTR: time to relapse. #: t-test was used to compare miRNA levels with variables with two values and ANOVA for variables with more than two values; ¶: adenocarcinoma was compared only with squamous cell carcinoma.