TABLE 1 Definitions of indicator conditions and recommendations for HIV testing
Category ICategory IICategory III
Conditions which are AIDS defining among people living with HIVConditions associated with an undiagnosed HIV prevalence of ≥0.1%Other conditions considered likely to have an undiagnosed HIV prevalence of >0.1%Conditions for which not identifying the presence of HIV infection may have significant adverse implications for the individual's clinical management
Strongly recommend testing
 Neoplasms
  Cervical cancer
  Lymphoma, non-Hodgkin
  Kaposi's sarcoma
 Bacterial infections
  Tuberculosis
  MAC lung disease
  Pneumonia, recurrent
  Salmonella septicaemia, recurrent
 Viral infections
  Cytomegalovirus retinitis
  Cytomegalovirus other (except liver, spleen, glands)
  Herpes simplex, ulcer(s) >1 month/bronchitis/pneumonitis
  Progressive multifocal leucoencephalopathy
 Parasitic infections
  Cerebral toxoplasmosis
  Cryptosporidosis diarrhoea, >1 month
  Microsporidiosis, >1 month
  Isosporiasis, >1 month
 Fungal infections
  Pneumocystis jiroveci
  Candidiasis, oesophageal
  Candidiasis, bronchial/tracheal/lungs
  Cryptococcosis, extra-pulmonary
  Histoplasmosis, disseminated/extra pulmonary
  Coccidiodomycosis, disseminated/extra pulmonary
Strongly recommend testing
 Sexually transmitted infections
 Malignant lymphoma
 Anal cancer/dysplasia
 Cervical dysplasia
 Herpes zoster
 Hepatitis B or C (acute or chronic)
 Mononucleosis-like illness
 Unexplained leukocytopenia/thrombocytopenia lasting >4 weeks
 Seborrhoeic dermatitis/exanthema
 Invasive pneumococcal disease
 Fever of unknown origin
 Non-genital Candidiasis
 Community-acquired pneumonia
 Nosocomial diarrhoea
 Pregnancy (implications for the unborn child)
Offer testing
 Primary lung cancer
 Lymphocytic meningitis
 Visceral leishmaniasis
 Hairy leukoplakia
 Severe or recalcitrant psoriasis
 Guillain–Barré syndrome
 Mononeuritis
 Subcortical dementia
 Multiplesclerosis-like disease
 Peripheral neuropathy
 Unexplained weight loss
 Unexplained lymphadenopathy
 Unexplained oral candidiasis
 Unexplained chronic diarrhoea
 Unexplained chronic renal impairment
Offer testing
 Conditions requiring aggressive immuno-suppressive therapy
  Cancer
  Transplantation
  Auto-immune disease treated  with immunosuppressive  therapy
 Primary space occupying lesion of the brain
 Thrombotic thrombocytopenic purpura?