TABLE 1 Definitions of indicator conditions and recommendations for HIV testing
Category ICategory IICategory III
Conditions which are AIDS defining among people living with HIVConditions associated with an undiagnosed HIV prevalence of ≥0.1%Other conditions considered likely to have an undiagnosed HIV prevalence of >0.1%Conditions for which not identifying the presence of HIV infection may have significant adverse implications for the individual's clinical management
Strongly recommend testing
  Cervical cancer
  Lymphoma, non-Hodgkin
  Kaposi's sarcoma
 Bacterial infections
  MAC lung disease
  Pneumonia, recurrent
  Salmonella septicaemia, recurrent
 Viral infections
  Cytomegalovirus retinitis
  Cytomegalovirus other (except liver, spleen, glands)
  Herpes simplex, ulcer(s) >1 month/bronchitis/pneumonitis
  Progressive multifocal leucoencephalopathy
 Parasitic infections
  Cerebral toxoplasmosis
  Cryptosporidosis diarrhoea, >1 month
  Microsporidiosis, >1 month
  Isosporiasis, >1 month
 Fungal infections
  Pneumocystis jiroveci
  Candidiasis, oesophageal
  Candidiasis, bronchial/tracheal/lungs
  Cryptococcosis, extra-pulmonary
  Histoplasmosis, disseminated/extra pulmonary
  Coccidiodomycosis, disseminated/extra pulmonary
Strongly recommend testing
 Sexually transmitted infections
 Malignant lymphoma
 Anal cancer/dysplasia
 Cervical dysplasia
 Herpes zoster
 Hepatitis B or C (acute or chronic)
 Mononucleosis-like illness
 Unexplained leukocytopenia/thrombocytopenia lasting >4 weeks
 Seborrhoeic dermatitis/exanthema
 Invasive pneumococcal disease
 Fever of unknown origin
 Non-genital Candidiasis
 Community-acquired pneumonia
 Nosocomial diarrhoea
 Pregnancy (implications for the unborn child)
Offer testing
 Primary lung cancer
 Lymphocytic meningitis
 Visceral leishmaniasis
 Hairy leukoplakia
 Severe or recalcitrant psoriasis
 Guillain–Barré syndrome
 Subcortical dementia
 Multiplesclerosis-like disease
 Peripheral neuropathy
 Unexplained weight loss
 Unexplained lymphadenopathy
 Unexplained oral candidiasis
 Unexplained chronic diarrhoea
 Unexplained chronic renal impairment
Offer testing
 Conditions requiring aggressive immuno-suppressive therapy
  Auto-immune disease treated  with immunosuppressive  therapy
 Primary space occupying lesion of the brain
 Thrombotic thrombocytopenic purpura?