ILD | Controls | p-value | |
PImax kPa | 9.3±3.4 | 8.7±2.8 | 0.51 |
PEmax kPa | 14.2±5.5 | 15.8±4.7 | 0.30 |
P0.1 kPa | 0.3 (0.3–0.5) | 0.2 (0.1–0.3) | 0.01 |
P0.1/PImax % | 4.0 (2–7) | 2.0 (0–3) | 0.006 |
fR L·min−1 | 21±6# | 18±5 | 0.04 |
VT L | 0.73±0.28# | 0.75±0.27 | 0.80 |
P0.1×ti/VT kPa·s·L−1 | 0.56 (0.4–0.61)# | 0.38 (0.28–0.51)¶ | 0.049 |
SnPna kPa | 8.6 (7.3–9.8) | 8.3 (6.3–10.3) | 0.99 |
TwPmo kPa | 0.86±0.4 | 1.32±0.4 | <0.001 |
TwPoes kPa | 0.92±0.4+ | 1.15±0.3§ | 0.17 |
TwPga kPa | -0.47±0.3+ | -0.77±0.2§ | 0.01 |
TwPdi kPa | 1.32±0.6+ | 1.88±0.5§ | 0.02 |
ttrig-max ms | 129±16 | 139±11 | 0.049 |
Hand-grip force | |||
Right kPa | 107±20ƒ | 116±40## | 0.66 |
Left kPa | 103±25ƒ | 108±35## | 0.76 |
Data are presented as median (interquartile range) or mean±sd, unless otherwise stated. ILD: interstitial lung disease; PImax: maximal inspiratory mouth occlusion pressure; PEmax: maximal expiratory mouth occlusion pressure; P0.1: mouth occlusion pressure 0.1 s after the onset of inspiration; fR: respiratory frequency; VT: tidal volume; ti: inspiratory time; SnPna: sniff nasal pressure; TwPmo: twitch mouth pressure; TwPoes: twitch oesophageal pressure; TwPga: twitch gastric pressure; TwPdi: twitch transdiaphragmatic pressure; ttrig-max: time between trigger impulse and maximum TwPmo. #: n=20; ¶: n=17;+: n=10; §: n=11; ƒ: n=22; ##: n=5.