Table 1– Summary of the seven reviewed cases
CaseFirst author [ref.]VaccineSexAge yrsOnset of ILD dayPrevious illnessSymptomsChest CTTreatmentOutcome
1Johnston [4]NAM5810Pneumothoraces (after lobectomy), arthritis, AMI, nephrolithiasisFever, dyspnoea, weight lossNACorticosteroidsSurvival
2Heinrichs [5]2009, seasonalF596Extrinsic allergic alveolitis to parakeetsFever, dyspnoea, joint painBilateral GGO, patchy infiltrationCorticosteroidsSurvival
3Kanemitsu [6]2009, seasonalM741GERDFever, dry coughBilateral patchy infiltrationCorticosteroidsSurvival
4Bhurayanontachai [7]2009, H1N1F381NoneDyspnoea, myalgiaBilateral lung infiltrationNA (aggressive treatment)Survival
5Umeda [8]2009, H1N1M572Idiopathic pulmonary fibrosisFever, dyspnoeaBilateral GGOCorticosteroids, CPA, CyA, sivelestat, PMX-DHPSurvival
6Kumamoto [9]2009, H1N1M612Lung cancer (after lobectomy and chemotherapy)Fever, dyspnoea, dry coughBilateral GGOCorticosteroidsSurvival
7Present study2011, seasonalF757Blood pressure, diabetes, dialysisFeverBilateral patchy infiltrationCorticosteroidsSurvival
  • ILD: interstitial lung disease; CT: computed tomography; AMI: acute myocardial infarction; GERD: gastro-oesophageal reflux disease; GGO: ground-glass opacities; NA: not available; CPA: cyclophosphamide; CyA: cyclosporine A; PMX-DHP: polymyxin-B direct hemoperfusion.