Table 4– Calculations of membrane diffusing capacity for nitric oxide (DM,NO), membrane diffusing capacity for carbon monoxide (DM,CO) and pulmonary capillary volume (Vc); see Appendix for explanation and commentary
 Data set DM,NO mL·min−1·mmHg−1 DM,CO# mL·min−1·mmHg−1 1/DM,CO mL−1·min·mmHg 1/Θbl,CO·Vc mL−1·min· mmHg 1/Θbl,CO mL−1·min mmHg·mL−1 Vc mL 1/Θbl,CO·Vc/(1/TL,CO) ∼ TL,CO red blood cell resistance % Comment NO blood resistance=0 1/Θbl,NO = 0 A 144 73 0.0137 0.0173 1.31 76 55 Most used Θbl value but at pH 8.0 [3] B 144 73 0.0137 0.0173 1.71 99 55 Θbl value at pH 7.4 [15] C 144 73 0.0137 0.0173 0.82 47 55 Θbl thin film exps [16] Finite NO blood resistance (1/Θbl,NO·Vc)/(1/TL,NO) = 37% D 230 117 0.0086 0.0224 1.31 58 72 DM,NO from [10]: E 230 117 0.0086 0.0224 1.71 76 72 DM,NO from [10]: F 230 117 0.0086 0.0224 0.82 37 72 DM,NO from [10]: G 230 0.0026¶ 0.22+ 88 36§ From Roughton–Forster equation and 1/DM,NO and 1/Θbl,NO
• The calculations for DM,CO and Vc were derived from “normal, resting” transfer factor of the lung for NO (TL,NO; 144 mL·min−1·mmHg−1) and TL,NO/TL,CO ratio (4.5) [1, 12, 19, 2226] (TL,CO=32 mL min−1 mmHg−1); for situations where NO uptake blood resistance is zero (1/DM,NO = 1/TL,NO) or finite (1/DM,NO<1/TL,NO). DM,CO derived from DM,NO for α = 1.97 (NO/CO diffusivity ratio), and Vc derived via Roughton–Forster equation 1 for different experimental values of the blood resistance to carbon monoxide transfer (1/Θbl,CO; at PO2 100 mmHg). Multiply by three to convert to SI units (mmol·min−1·kPa−11) from mL·min−1·mmHg−1. #: α = 1.97; : 1/Θbl,NO·Vc was used not 1/Θbl,CO·Vc; +: 1/Θbl,NO was used not 1/Θbl,CO; §: ∼NO red blood cell resistance % was used not TL,CO red blood cell resistance %.