| Characteristics | Part A | Part B |
| Participants n | 42 | 15 |
| Age years | 73±8 | 75±8 |
| Females | 15 (36) | 8 (53) |
| Body mass index kg·m−2 | 27.4±5 | 26.7±4 |
| FEV1 L | 1.4±0.5 | 1.4±0.4 |
| FEV1 % pred | 59±16 | 63±14 |
| FVC L | 3.0±1 | 3.0±1 |
| FVC % pred | 102±23 | 102±22 |
| FEV1/FVC % | 47±13 | 50±15 |
| TLC % pred | 103±16 | 101±14 |
| FRC % pred | 123±30 | 113±33 |
| RV % pred | 124±36 | 118±34 |
| RV/TLC | 0.5±0.1 | 0.5±0.1 |
| DLCO % pred | 55±16 | 58±9 |
| Comorbidities % of total participants | ||
| Coronary heart disease | 33 | 13 |
| Systemic hypertension | 55 | 27 |
| Diabetes | 21 | 13 |
| Dyslipidaemia | 38 | 13 |
| Osteoarthritis | 60 | 73 |
| Osteoporosis | 10 | 7 |
| Absence of co-morbidities | 10 | 20 |
| With 1 comorbidities | 14 | 27 |
| With ≥2 comorbidities | 76 | 53 |
Data are presented as mean±sd or n (%), unless otherwise stated. FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity; TLC: total lung capacity; FRC: functional residual volume; RV: residual volume; DLCO: diffusion capacity of the lung for carbon monoxide.