Table 1– Patient characteristics
TotalSSEA-4 positiveSSEA-4 negativep-value
Subjects381424
Sex
 Female7 (18)2 (14)5 (21)0.615
 Male31 (82)12 (86)19 (79)
 Age yrs66.0±8.261.9±7.60.143
ECOG#
 028 (74)11 (79)17 (71)0.601
 ≥110 (26)3 (21)7 (29)
UICC stage
 IA6 (16)2 (14)4 (17)0.899
 IB13 (34)4 (29)9 (37)
 IIA8 (21)3 (21)5 (21)
 IIB11 (29)5 (36)6 (25)
pT
 T110 (26)4 (29)6 (25)0.809
 T228 (74)10 (71)18 (75)
pN
 N021 (55)7 (50%)14 (58)0.618
 N117 (45)7 (50%)10 (42)
Type of resection
 Pneumonectomy6 (16)4 (29)2 (8)0.247
 Bilobectomy4 (10)1 (7)3 (13)
 Lobectomy28 (74)9 (64)19 (79)
Relapse %
 Total16 (42)11 (79)5 (21)0.000
 Local1 (3)0 (0)1 (4)NA
 Distant15 (39)11 (79)4 (17)NA
Mortality %
 Total14 (37)9 (64)5 (21)0.011
 Yes13 (34)9 (64)4 (17)NA
 No1 (3)0 (0)1 (4)NA
Disease-free survival monthsNR11.1 (4.3–45.1)NRNA
Overall survival monthsNR45.0 (14.5–NR)NRNA
Survival rate %
 1-yr91.7 (82.7–100)85.1 (66.0–100)95.7 (87.3–100)NA
 2-yr83.0 (70.6–95.5)69.6 (44.7–94.6)90.9 (78.7–100)
 5-yr61.9 (44.4–79.4)35.4 (8.1–62.7)80.1 (64.4–97.8)
Follow-up months72.9 (42.7–91.5)91.4 (42.7–96.3)70.2 (37.5–84.2)NA
  • Data are presented as n, n (%), mean±sem or median (95% CI), unless otherwise stated. SSEA-4: stage-specific embryonic antigen-4; ECOG: Eastern Cooperative Oncology Group; UICC: Union Internationale Contre le Cancer; NR: not reached; NA: not applicable. p-values in bold are statistically significant. #: ECOG 0 is a patient without physical restriction and ECOG≥1 is a patient with increasing physical restriction. Bold indicates statistical significance.