Table 4– Univariate regression analysis to identify predictors for diastolic dysfunction

Variable	p-value^#	OR (95% CI)	R^2¶
Age yrs	<0.001	1.136 (1.093–1.180)	0.193
Female	0.663	0.910 (0.597–1.389)	0.001
Sleep apnoea (AHI ≥15 events·h⁻¹)	0.004	2.221 (1.290–3.827)	0.033
AHI events·h⁻¹	0.001	1.041 (1.017–1.065)	0.052
Desaturation index %	0.003	1.031 (1.011–1.052)	0.003
Hypertension	0.487	1.257 (0.659–2.397)	0.002
Diabetes	0.149	1.563 (0.853–2.865)	0.008
Coronary artery disease	0.092	1.676 (0.919–3.058)	0.011
Left ventricular mass g	0.021	1.004 (1.001–1.007)	0.021
LVEDD	0.442	1.015 (0.977–1.054)	0.002
BMI kg·m⁻²	0.005	1.075 (1.022–1.130)	0.032
Cardiac frequency beats·min⁻¹	0.010	1.024 (1.006–1.042)	0.026
Systolic blood pressure mmHg	0.196	1.007 (0.996–1.018)	0.006
Diastolic blood pressure mmHg	0.391	0.992 (0.974–1.010)	0.003
AT1 antagonists	0.032	1.966 (1.060–3.647)	0.018
Calcium channel blockers	0.718	0.925 (0.606–1.412)	0.000
Diuretics	0.044	1.547 (1.012–2.365)	0.016
Loop diuretics	0.181	1.809 (0.759–4.311)	0.007
Thiazide	0.063	1.501 (0.979–2.300)	0.013
Other diuretics	0.233	1.828 (0.678–4.925)	0.006
Number of antihypertensives	0.080	1.161 (0.982–1.372)	0.012

AHI: apnoea/hypopnoea index; LVEDD: left ventricular end-diastolic diameter; BMI: body mass index; AT1: angiotensin receptor 1. ^#: univariate analysis; ^¶: Nagelkerkes R².