Table 1– Demographic and pulmonary function data in 98 chronic obstructive pulmonary disease patients according to mean pulmonary artery pressure at rest
VariablesNon-PHPH
Subjects7226
Age years64±662±8
Males %5342
BMI kg·m−224±525±6
BSA m21.8±0.21.8±0.3
SBP mmHg139±22140±18
DBP mmHg69±1268±13
fC beats·min−174±1284±13*
GFR mL·min−190±35109±45
NT-proBNP# pmol·L−113±1216±17
Diabetes54
Systemic hypertension2211
Former/current smokers %68/3269/31
Pack-years41±1939±20
Haemoglobin g·dL−114.514.2
CO-Hb %2.4±1.22.6±1.4
GOLD stages II/III/IV35/23/142/8/16*
Respiratory failure69
FEV1 % pred46±1532±12*
FVC % pred76±2061±16*
FEV1/FVC %49±1143±13*
DLCO % pred57±1936±20*
TLC % pred119±29128±36
RV/TLC %59±1167±9
RV % pred192±59241±60*
Normoxaemia/hypoxaemia+ %50/40/1015/50/35
6MWD m489±113343±149*
Presence of emphysema§69 (96)26 (100)
  • Values are presented as n, mean±sd or n (%), unless otherwise stated. PH: pulmonary hypertension; BMI: body mass index; BSA: body surface area; SBP: systolic blood pressure; DBP: diastolic blood pressure; fC: cardiac frequency; GFR: glomerular filtration rate; NT-proBNP: N-terminal pro-brain natriuretic peptide; CO-Hb: carboxyhaemoglobin; GOLD: Global Initiative for Chronic Obstructive Lung Disease; FEV1: forced expiratory volume in 1 s; % pred: % predicted; FVC: forced vital capacity; DLCO: diffusing capacity of the lung for carbon monoxide; TLC: total lung capacity; RV: residual volume; 6MWD: 6-min walk distance. #: log-transformed data; : DLCO was not measured in 11%; +: normoxic arterial oxygen tension (PaO2)>10.0 kPa, mildly hypoxic PaO2 8.1–10.0 kPa and moderately hypoxic PaO2 <8.0 kPa; §: by high-resolution computed tomography. *: p<0.05 versus non-PH (p<0.05).