Table 2– Radiological and clinical outcomes
CV-CV+
AllRespondersNonrespondersAllNonrespondersResponders
Subjects n51361529245
TLVR %55.7 (18.0–92.4)72.1 (49.8–98.7)6.4 (2.0–13.5)5.7 (1.6–16.0)3.75 (0.3–8.7)99.2 (40.8–99.6)
TLVR mL752.7 (218.2–1,270)1061.4 (736.2–1882.2)132.5 (38.6–187.6)98.6 (26.8–232.1)62.2 (3.9–166.2)1603.8 (837.1–2216.9)
FEV1
 Pre-operative L0.87±0.360.87±0.350.88±0.390.82±0.320.79±0.331.00±0.27
 Post-operative L1.01±0.451.07±0.460.89±0.400.83±0.340.75±0.271.23±0.36
 Absolute change0.14±0.200.19±0.210.01±0.070.01±0.21−0.04±0.190.23±0.12
 Percentage change16±2223±242±81±15−3±1223±10
 Reached MCID22 (43)21 (58)1 (7)6 (21)2 (8)4 (80)
6MWT#
 Pre-operative m327±117324±108335±140298±97299±102291±84
 Post-operative m353±111358±106342±125307±92304±87322±120
 Difference m24±5731±567±5610±575±5632±65
 Reached MCID22 (45)18(53)4 (27)12 (44)9 (41)3 (60)
SGRQ
 Pre-operative points63±1264±1260±1163±1363±1364±13
 Post-operative points51±1848±1957±1558±1858±1659±27
 Difference points−10±13−13±14−2±8−5±15−4±15−12±19
 Reached MCID25(68)19 (73)6 (54)11 (50)9 (50)2 (67)
Other
 Total lung capacity L7.39±1.677.24±1.687.73±1.657.56±1.417.76±1.376.61±1.33
 Residual volume4.49±1.224.29±1.184.97±1.194.93±1.535.28±1.443.25±0.41
  • Data are presented as median (interquartile range), mean±sd or n (%), unless otherwise stated. CV-: collateral ventilation absent; CV+: collateral ventilation present; TLVR: target lobe volume reduction; FEV1: forced expiratory volume in 1 s; MCID: minimal clinically important difference; 6MWT: 6-min walking test; SGRQ: St. George′s Respiratory Questionnaire. MCID is defined as an improvement of ≥15% in FEV1, an improvement of ≥26 m in the 6MWT and an improvement (i.e. decrease) of ≥4 points on the SGRQ. #: CV-all (n=49); CV-responders (n=34); CV-nonresponders (n=15); CV+all (n=27); CV+nonresponders (n=22); CV+responders (n=5). : CV-all (n=37); CV-responders (n=26); CV-nonresponders (n=11); CV+all (n=21); CV+nonresponders (n=18); CV+responders (n=3).