Table 1– Anthropometric characteristics and resting pulmonary function testing in pulmonary arterial hypertension (PAH) patients and in controls
PAHControls
Female/male n15/105/5
Age yrs38±1239±16
Height cm168±8171±9
BMI kg·m−224±323±4
FEV1 L (% pred)3.0±0.8* (91±16)*4.0±0.7 (116±11)
FVC L (% pred)3.6±1.0* (93±17)*4.7±0.8 (116±10)
FEV1/VC# %115±10110±5
TLC L (% pred)5.3±1.1* (93±10)*6.4±0.9 (107±9)
VC L (% pred)3.7±1.1* (94±17)*4.7±0.8 (113±10)
FRC L (% pred)2.8±0.6 (95±14)3.2±0.7 (104±16)
IC L (% pred)2.5±0.8* (93±20)*3.2±0.4 (108±18)
RV L (% pred)1.6±0.4 (97±23)1.7±0.5 (95±17)
ERV L (% pred)1.2±0.5 (93±36)1.5±0.6 (115±34)
FEF25% L·s−1 (% pred)6.7±1.7 (100±16)7.6±1.8 (108±10)
FEF50% L·s−1 (% pred)4.0±1.2* (89±20)*5.1±1.0 (109±18)
FEF75% L·s−1 (% pred)1.4±0.7* (69±25)*2.2±0.7 (105±8)
  • Data are presented as mean±sd, unless otherwise stated. BMI: body mass index; FEV1: forced expiratory volume in 1 s; % pred: % predicted; FVC: forced vital capacity; TLC: total lung capacity; VC: vital capacity; FRC: functional residual capacity; IC: inspiratory capacity; RV: residual volume; ERV: expiratory reserve volume; FEF25%, 50% and 75%: forced expiratory flow at 25%, 50% and 75%, respectively, of the FVC. #: spirometric evidence of an obstructive ventilatory defect as defined by a reduced FEV1/VC ratio below the fifth percentile of the predicted value [15]. *: p<0.05, overall PAH versus healthy.