COPD | Control subjects | p-value | |
Demographics | |||
Subjects n | 10 | 10 | |
Age yrs | 66.8±7.5 | 64.7±12.4 | |
Males | 100 | 100 | |
Height m | 1.76±0.05 | 1.77±0.08 | ns |
Weight kg | 85.4±12.4 | 90.1±21.2 | ns |
Body mass index kg·m−2 | 27.6±3.2 | 28.3±4.6 | ns |
Current smoker | 10 | 0 | |
Former smoker | 90 | 90 | |
Pack-yrs | 46.5±18.3 | 23.9±12.2 | 0.006 |
GOLD classification | |||
I | 20 | 0 | |
II | 50 | 0 | |
III | 30 | 0 | |
IV | 0 | 0 | |
Lung function | |||
FVC % pred | 77±18 | 86±9 | ns |
FEV1 % pred | 62±20 | 86±8 | 0.008 |
FEV1/FVC % pred | 60±9 | 79±9 | 0.001 |
Total lung capacity % pred | 100±13 | 90±11 | ns |
Residual volume % pred | 151±29 | 106±17 | 0.003 |
Blood parameters | |||
C-reactive protein mg·dL−1 | 0.46±0.31 | 0.50±0.28 | ns |
White blood cell count cells·L−1 | 8.14±3.34 | 7.22±2.70 | ns |
Coronary artery disease | |||
1 vessel | 30 | 10 | |
2 vessels | 0 | 10 | |
3 vessels | 70 | 80 |
Data are presented as mean±sd or %, unless otherwise stated. GOLD: Global Initiative for Chronic Obstructive Lung Disease; FVC: forced vital capacity; % pred: % predicted; FEV1: forced expiratory volume in 1 s; ns: not significant.