Genotypes | ||||||
YA/YA | XA/YA | XA/XA | XA/O | XA/O+O/O | A/O+O/O | |
P-CAP versus controls | 1.43 (1.11–1.84); 0.006 | 0.62 (0.47–0.87); 0.005 | ||||
ICU versus general ward | 1.93 (1.02–3.65); 0.040 | |||||
SSh versus no SSh | 2.83 (1.28–6.27); 0.008 | 2.19 (1.11–4.29); 0.021 | 1.70 (1.02–2.82); 0.040 | |||
SSh+SS versus NSS | 0.19 (0.04–0.85); 0.015 | 1.55 (1.00–2.40); 0.048 | ||||
Acute renal failure versus no acute renal failure | 1.62 (1.03–2.58); 0.037 | |||||
ARF versus no ARF | 0.43 (0.24–0.76); 0.0003 | |||||
MODS versus no MODS | 0.43 (0.24–0.76); 0.003 | 2.15 (1.08–4.26); 0.026 | 2.13 (1.27–3.59); 0.004 | |||
PSI IV-V versus I–III | 0.12 (0.03–0.56); 0.001 | 2.34 (1.16–4.72); 0.015 | 1.61 (1.03–2.52); 0.036 |
Data are presented as OR (95% CI); p-value. Values are uncorrected p-value for the bivariate comparison, except for the susceptibility analysis, where values correspond to conditional estimates. P-CAP: pneumococcal community-acquired pneumonia; ICU: intensive care unit; SSh: septic shock; SS: severe sepsis; NSS: non-severe sepsis, includes patients without either severe sepsis or septic shock; ARF: acute respiratory failure; MODS: multi-organ dysfunction syndrome; PSI: pneumonia severity index.