Table 1– Facultative glucose transporter (GLUT) and sodium-coupled glucose transporter (SGLT) expression in human cultured epithelial cells, human bronchial tissue and whole lung
TransporterHuman cultured epithelial cellsBronchial tissueWhole lung
H441HBECs
NonpolarisedPolarised
mRNAProteinmRNAProteinmRNAProteinmRNAProteinmRNAProtein
GLUTs
 GLUT1+ [13]- [13]- [13]+ [11]+ [11]+ [11]- [45]+ [47]- [45, 46]
 GLUT2+ [13]+ [13]+ [10, 13]+ [11]- [11]+ [11]+ [13, 46]
 GLUT3- [13]- [13]- [13]+ [11]- [11]+ [11]- [45]+ [47]- [45, 46]
 GLUT4+ [13]+ [13]- [13]+ [11]- [11]+ [11]- [45]- [45, 46]
 GLUT5+ [11]+ [11]- [45]+ [47]- [45, 46]
 GLUT6+ [11]+ [11]
 GLUT7+ [11]+ [11]
 GLUT8+ [11]- [11]+ [11]
 GLUT9+ [11]+ [11]
 GLUT10+ [10]+ [11]+ [11]+ [11]+ [48]
 GLUT11+ [11]+ [11]
 GLUT12+ [11]+ [11]
SGLTs
 SGLT1+ [11]- [11]+ [11]+ [49]
 SGLT2+ [11]- [11]+ [11]+ [49]
  • HBEC: human bronchial epithelial cells; +: present; -: absent.