Table 6– Comparison of relevant haplotypes encompassing SFTPD, SFTPA1, SFTPA2 and MBL2 between pneumococcal community-acquired pneumonia (P-CAP) patients and controls
HaplotypeP-CAP#ControlsOR (CI 95%)p-value+
XA48 (16.1)388 (21.2)0.72 (0.51–0.99)0.053
6A2158 (53.0)1088 (59.4)0.60 (0.57–0.99)0.042
1A0150 (50.3)1069 (58.4)0.72 (0.57–0.93)0.010
6A2-XA23 (7.7)205 (11.2)0.66 (0.42–1.04)0.085
1A0-XA21 (7.0)207 (11.3)0.60 (0.37–0.95)0.033
6A2-1A0131 (44.0)940 (51.5)0.74 (0.58–0.95)0.021
6A2-1A0 -XA18 (6.0)185 (10.1)0.57 (0.35–0.94)0.033
C-6A2-1A0-XA3 (1.0)80 (4.4)0.22 (0.07–0.71)0.005
  • Data are presented as the n chromosomes (%), unless otherwise stated. Only relevant haplotypes are shown. MBL2: mannose-binding lectin 2 gene. #: n=298; : n=1832; +: uncorrected for the bivariate comparison of haplotypes.