Table 5– Pairwise linkage disequilibrium measure (D') for surfactant proteins A1, A2 and D alleles with regard to mannose-binding lectin (MBL) alleles from 748 healthy controls
MBL2
YBYCYDXAYA
SFTPA1
6A
6A20.53 (<0.0001)0.55 (0.033)0.74 (<0.001)0.31 (0.001)
6A30.37 (0.039)0.78 (0.006)
6A41 (0.003)
SFTPA2
1A00.45 (<0.001)0.71 (0.003)0.76 (<0.001)0.37 (<0.001)
1A11 (0.037)0.42 (0.026)
 SP-D
  • Data are presented as D' (p-value). D' values <0.3 or with a corresponding p-value >0.05 have not been considered. Linkage disequilibrium was measured using Arlequin 3.11 software. Only relevant haplotypes are shown. MBL2: mannose-binding lectin 2 gene.