Table 1– Leicester cough questionnaire (LCQ) scores, visual analogue scale (VAS) score and citric acid challenge data
Visit 1
Visit 2
Visit 3
On CPAP at 1 yr
LCQ domains
Cough challenge
 C2 mM35.77.81>1000
 C5 mM42.440.7>1000
  • Assessments were performed on continuous positive airway pressure (CPAP) following initiation of therapy, off CPAP for 1 week and on CPAP at 1 yr of follow up. The LCQ is a health-related quality of life measure of chronic cough and is divided into three domains. Total LCQ scores range from 3 to 21, with higher scores representing better quality of life. The VAS was a 100-mm linear scale. Cough challenges were undertaken with citric acid. C2 is the concentration of citric acid eliciting two or more coughs and C5 that eliciting five or more coughs.