Table 7– Logistic regression analysis of predictors of the exacerbation-prone phenotype in severe asthma
Predictor variableOR for frequent exacerbations (95% CI)p-value
ACQ score#1.227 (0.628–2.4)0.549
Sex2.618 (0.781–8.783)0.119
BMI kg·m−21.027 (0.939–1.123)0.562
SampEn R5R203.23 (1.242–8.4)0.016
  • Logistic regression: having frequent exacerbations (two or more in the previous year) was compared with the baseline category of having infrequent exacerbations (fewer than two in the previous year). Odds ratios are for a one-point increase in Asthma Control Questionnaire (ACQ) score, for female sex compared with the baseline category of male sex, for a 1-kg·m−2 increase in body mass index (BMI) and for a 0.1 increase in sample entropy (SampEn) of resistance at 5 Hz (R5) minus resistance at 20 Hz (R20). #: on a scale of 0 (best) to 6 (worst).