Table 2– Baseline characteristics (at the time when pregnancy was discovered) of females who delivered a healthy baby and survived, of females with induced abortions, and of females who did not survive pregnancy or required transplantation
Females who delivered a healthy baby and survived without transplantationFemales with induced abortionsFemales who died or required transplantation
Subjects1664
Age yrs#30±531±533±4
NYHA FC#
 I/II12 (75)4 (67)1 (25)
 III4 (25)2 (33)1 (25)
 IV002 (50)
6MWD m485±118467±35234±202
Type of PAH
 Idiopathic10 (63)3 (50)4 (100)
 Connective tissue disease4 (25)00
 Congenital heart disease1 (6)00
 HIV infection associated03 (50)0
 Portopulmonary1 (6)00
Haemodynamics+
Pra mmHg4±36±211±3
 mPAP mmHg36±1548±1871±5
Ppcw mmHg6±36±27±2
 CI L·min−1·m−23.2±0.93.4±1.02.0±0.3
 PVR dyn·s−1·cm−5500±352765±5981667±209
 Sv,O2 %66±1169±1258±3
PAH medication#
 Oral anticoagulants841
 Calcium channel blockers (responders)800
 Intravenous epoprostenol320
 Subcutaneous treprostinil001
 Inhaled iloprost200
 Endothelin receptor antagonists241
 PDE-5 inhibitors430
  • Data are presented as n, mean±sd or n (%). NYHA FC: New York Heart Association functional class; 6MWD: 6-min walk distance; PAH: pulmonary arterial hypertension; Pra: right arterial pressure; mPAP: mean pulmonary artery pressure; Ppcw: pulmonary capillary wedge pressure; CI: cardiac index; PVR: pulmonary vascular resistance; Sv,O2: mixed venous oxygen saturation; PDE: phosphodiesterase. #: at the time pregnancy was discovered; : 6MWD was set to 0 m in NYHA FC IV patients unable to walk (n=2); +: most recent variables at the time pregnancy was discovered.