Table 1– Baseline characteristics of patients with pulmonary arterial hypertension (PAH) and pregnancies
CharacteristicAll patients
Age yrs#31±5
 I/II16 (62)
 III8 (31)
 IV2 (7)
6MWD m472±97
Type of PAH
 Idiopathic17 (64)
 Connective tissue disease4 (16)
 Congenital heart disease1 (4)
 HIV infection associated3 (12)
 Portopulmonary1 (4)
Pra mmHg6±4
 mPAP mmHg44±19
Ppcw mmHg6±2
 CI L·min−1·m−23.1±0.9
 PVR dyn·s−1·cm−5741±571
PAH medication#
 Oral anticoagulants13
 Calcium channel blockers (responders)8
 Intravenous epoprostenol5
 Subcutaneous treprostinil1
 Inhaled iloprost2
 Endothelin receptor antagonists7
 PDE-5 inhibitors7
 No PAH medication4+
  • Data are presented as n, mean±sd or n (%). NYHA FC: New York Heart Association functional class; 6MWD: 6-min walk distance; Pra: right arterial pressure; mPAP: mean pulmonary artery pressure; Ppcw: pulmonary capillary wedge pressure; CI: cardiac index; PVR: pulmonary vascular resistance; Sv,O2: mixed venous oxygen saturation; PDE: phosphodiesterase. #: at the time pregnancy was discovered; : most recent variables at the time pregnancy was discovered; +: in these patients the diagnosis of PAH was made during pregnancy.