| Toxicity | Patients hospitalised with toxicity-related diagnoses | OR (95% CI)# | OR (95% CI) adjusted for propensity scores | |
| RT alone | CRT | |||
| Infection | 104 (4.8) | 73 (8.7) | 1.9 (1.4–2.6) | 2.0 (1.4–2.8) |
| Neutropenia | ≤11(<0.5)¶ | >50 (>5.5) | 24.6 (10.5–57.3) | 21.5 (9.0–51.4) |
| Fever | 12 (0.6) | 12 (1.4) | 2.6 (1.2–5.8) | 2.1 (0.9–5.2) |
| Dehydration | 132 (6.1) | 92 (10.9) | 1.9 (1.4–2.5) | 1.8 (1.4–2.5) |
| Nausea/emesis | 19 (0.9) | 25 (3.0) | 3.4 (1.9–6.3) | 3.1 (1.6–5.8) |
| Anaemia | 105 (4.8) | 108 (12.8) | 2.9 (2.2–3.8) | 2.8 (2.1–3.9) |
| Thrombocytopenia | ≤11 (<0.5) | ≤11 (<1.0) | 6.9 (1.8–26.0) | 11.5 (2.9–45.7) |
| Renal dysfunction | 22 (1.0) | 13 (1.5) | 1.5 (0.7–3.0) | 1.6 (0.8–3.4) |
| Unspecified adverse events of systemic therapy | ≤11 (<0.5) | <15 (<2.0) | 36.5 (4.8–277.6) | 30.8 (3.9–243.4) |
Data are presented as n (%), unless otherwise stated. #: odds ratio for toxicity-related hospitalisation among patients treated with CRT compared with those treated with RT alone; ¶: because of Surveillance, Epidemiology and End Results registry linked to Medicare claims privacy rules, exact numbers are not reported for small subgroups, which might risk loss of confidentiality.