Non-purulent | Purulent | p-value | |
Subjects n | 34 | 39 | |
Temperature ≥38°C | 9 (26) | 12 (32) | 0.52 |
Respiratory rate breaths·min−1 | 25 (23–32) | 25 (24–32) | 0.93 |
Heart rate beats·min−1 | 98 (90–113) | 97 (88–110) | 0.78 |
Type of exacerbation (Anthonisen criteria) | |||
Type I | 0 | 32 (82) | <0.0001 |
Type II | 18 (53) | 7 (18) | 0.076 |
Type III | 16 (47) | 0 | 0.001 |
Leukocyte count ×109 cells·L−1 | 8.82 (7–11) | 10.54 (8.4–12.7) | 0.19 |
CRP on admission mg·dL−1 | 5.3 (0.10–23.0) | 11.6 (0.10–33.0) | 0.006 |
CRP on day 3 mg·dL−1 | 1.2 (0.10–15.6) | 2.7 (0.10–18.1) | 0.01 |
PCT on admission ng·mL−1 | 0.04 (0.01–0.10) | 0.05 (0.02–0.13) | 0.89 |
PCT <0.1 ng·mL−1 | 24 (46) | 28 (54) | |
PCT 0.1–0.25 ng·mL−1 | 4 (36) | 7 (63) | |
PCT >0.25 ng·mL−1 | 4 (40) | 6 (60) | |
PCT on day 3 ng·mL−1 | 0.03 (0.01–0.05) | 0.04 (0.02–0.07) | 0.32 |
CRP on admission mg·dL−1 | |||
Type I | 12.4 (0.80–26.2) | ||
Type II | 5.8 (0.10–22.1) | 8.7 (1.2–17.3) | 0.20 |
Type III | 2.9 (0.20–9.5) | ||
PCT on admission ng·mL−1 | |||
Type I | 0.08 (0.02–0.20) | ||
Type II | 0.03 (0.01–0.10) | 0.04 (0.02–0.10) | 0.49 |
Type III | 0.02 (0.01–0.10) | ||
pH | 7.39±0.06 | 7.41±0.05 | 0.15 |
Pa,CO2 mmHg | 45.1±12.3 | 39.5±6.4 | 0.14 |
Pa,O2 mmHg | 53.3±4.6 | 57.9±10.1 | 0.53 |
Data are presented as n (%), median (interquartile range) or mean±sd, unless otherwise stated. CRP: C-reactive protein; PCT: procalcitonin; Pa,CO2: arterial carbon dioxide tension; Pa,O2: arterial oxygen tension. p-values in bold are statistically significant.