Table 2– Clinical characteristics at admission
Non-purulentPurulentp-value
Subjects n3439
Temperature ≥38°C9 (26)12 (32)0.52
Respiratory rate breaths·min−125 (23–32)25 (24–32)0.93
Heart rate beats·min−198 (90–113)97 (88–110)0.78
Type of exacerbation (Anthonisen criteria)
 Type I032 (82)<0.0001
 Type II18 (53)7 (18)0.076
 Type III16 (47)00.001
Leukocyte count ×109 cells·L−18.82 (7–11)10.54 (8.4–12.7)0.19
CRP on admission mg·dL−15.3 (0.10–23.0)11.6 (0.10–33.0)0.006
CRP on day 3 mg·dL−11.2 (0.10–15.6)2.7 (0.10–18.1)0.01
PCT on admission ng·mL−10.04 (0.01–0.10)0.05 (0.02–0.13)0.89
 PCT <0.1 ng·mL−124 (46)28 (54)
 PCT 0.1–0.25 ng·mL−14 (36)7 (63)
 PCT >0.25 ng·mL−14 (40)6 (60)
PCT on day 3 ng·mL−10.03 (0.01–0.05)0.04 (0.02–0.07)0.32
CRP on admission mg·dL−1
 Type I12.4 (0.80–26.2)
 Type II5.8 (0.10–22.1)8.7 (1.2–17.3)0.20
 Type III2.9 (0.20–9.5)
PCT on admission ng·mL−1
 Type I0.08 (0.02–0.20)
 Type II0.03 (0.01–0.10)0.04 (0.02–0.10)0.49
 Type III0.02 (0.01–0.10)
pH7.39±0.067.41±0.050.15
Pa,CO2 mmHg45.1±12.339.5±6.40.14
Pa,O2 mmHg53.3±4.657.9±10.10.53
  • Data are presented as n (%), median (interquartile range) or mean±sd, unless otherwise stated. CRP: C-reactive protein; PCT: procalcitonin; Pa,CO2: arterial carbon dioxide tension; Pa,O2: arterial oxygen tension. p-values in bold are statistically significant.