Table 3– Multivariate mortality predictors and derivation of the Scottish composite score
VariablesCategoriesAdjusted HR (95% CI)Points
Age yrs≥702.20 (1.35–3.61)1
<70 (reference)0
SexMale2.01 (1.15–3.51)1
Female (reference)0
AetiologyCTD-PAH-SSc or Group I PAH others#2.33 (1.42–3.82)1
Idiopathic, heritable, anorexigen-associated PAH or CTD-PAH non-SSc0
6MWD m<505.04 (2.33–10.89)3
50–1493.45 (1.48–8.05)2
150–2992.48 (1.28–4.79)1
≥300 (reference)0
Pra mmHg≥101.50 (0.90–2.49)1
<10 (reference)0
CO L·min−1<32.18 (1.32–3.61)1
≥3 (reference)0
  • 6MWD: 6-min walk distance; Pra: right atrial pressure; CO: cardiac output; CTD-PAH: connective tissue disease associated pulmonary arterial hypertension (PAH); SSc: systemic sclerosis; #: includes portopulmonary hypertension, HIV and pulmonary veno-occlusive disease.