Table 5– Inter-patient variability of sputum inflammatory mediators and cell counts in matched stable patients with usual chronic obstructive pulmonary disease (COPD) and α1-antitrypsin deficiency (A1ATD)
IL-8MPOLTB4Sputum neutrophilsSputum macrophages
A1ATD78.9230.151.129.135.7
COPD99.378.3**71.120.658.0
  • Data are presented as coefficient of variance (CV) as %. The inter-patient (between patients) CV is derived from individual patient's mediator-specific mean and sd (from logged data), calculated using data from nine visits. IL: interleukin; MPO: myeloperoxidase; LTB4: leukotriene B4. **: p<0.01.