Table 1– Baseline characteristic for patients included in the study
CharacteristicsA1ATD groupUsual COPD
Subjects n1212
Age yrs50 (33–66)61 (57–67)**
Male9 (75)5 (42)
FVC L3.0±0.873.05±0.77
FEV1/FVC %30.4±9.237.1±8.9
TL,CO% pred49.2±11.658.9±15.2
BMI kg·m−223.9±3.8623.2±4.1
Current smokers2 (16.7)7 (58)
Pack-yr history29.0±18.238.5±17.7
Patients on long-acting bronchodilators11 (92)12 (100)
Patients on ICS6 (50)7 (58)
Patients on long-acting inhaled anti-muscurinics9 (75)10 (83)
Exacerbations in preceding year4 (2–5)3 (1–6)
  • Data are presented as median (interquartile range), n (%) or mean±sd, unless otherwise stated. A1ATD: α1-antitrypsin deficiency; COPD: chronic obstructive pulmonary disease; FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity; TL,CO: transfer factor of the lung for carbon monoxide; % pred: % predicted; BMI: body mass index; ICS: inhaled corticosteroids. **: p<0.01.