Imaging | |
Pleuroparenchymal thickening in upper zones | 12/12 |
Pleuroparenchymal thickness mm | 4–15 |
Other upper zone changes | |
Subjacent fibrosis | 12/12 |
Mean severity of fibrosis# | 2 |
ILD pattern in other zones | 6/12 |
Diffuse¶ PPFE | 1/12 |
NSIP+ | 1/12 |
NSIP/possible UIP§ | 3/12 |
Unclassifiable interstitial pneumoniaƒ | 1/12 |
Other features | |
PAH## | 1/12 |
Bronchiectasis | 1/12 |
Consolidation | 6/12 |
Asbestos-related calcified pleural plaques | 0/12 |
Pathology | |
Pleuroparenchymal fibrosis¶¶ | 12/12 |
Pleural fibrosis | 11/12 |
Interstitial elastosis | 12/12 |
IAF | 12/12 |
Other changes | |
Bronchocentric IAFE | 11/12 |
Perilobular IAFE | 6/12 |
Co-existent ILD in lower lobes | 7/7 |
IAFE | 3/7 |
IAFE and HP | 1/7 |
UIP | 3/7 |
Other features | |
Venous and arterial intimal fibrosis | 8/12 |
Granulomas | 3/12 |
Pleural ossification/calcification | 0/12 |
Data are presented as n/N or range, unless otherwise stated. ILD: interstitial lung disease; PPFE: pleuroparenchymal fibroelastosis; NSIP: nonspecific interstitial pneumonia; UIP: usual interstitial pneumonia; PAH: pulmonary arterial hypertension; IAF: intra-alveolar fibrosis; IAFE: intra-alveolar fibrosis and elastosis; HP: hypersensitivity pneumonitis. #: 1, minimal; 2, moderate; 3, severe. ¶: all zones. +: diffuse. §: lower zone, two out of 12; middle/lower zone, one out of 12. ƒ: middle/lower zone. ##: pulmonary/aorta ratio >1. ¶¶: data from upper lobe biopsies in 11 out of 12 patients; one patient had sampling of middle and lower lobes only.