No maternal asthma | Maternal asthma | p-value | |||
Birth weight# | |||||
Cotinine ng·mL−1 | |||||
<4 | 825 | Ref: 3383.87 g | 49 | Ref: 3305.81 g | |
4–20 | 574 | 7.98 (-32.12–48.07) | 59 | -110.13 (-245.82–25.56) | |
20–50 | 218 | -32.00 (-88.76–24.76) | 18 | 81.13 (-109.72–271.99) | |
>50 | 438 | -147.13 (-192.24– -102.02) | 36 | -114.95 (-270.80–40.90) | 0.097 |
SHS exposure¶ | |||||
No | 729 | 9.86 (-37.23–56.95) | 51 | -53.47 (-216.22–109.29) | |
Only outside the home | 494 | 11.18 (-39.29–61.65) | 39 | -108.11 (-282.13–65.91) | |
Inside the home | 389 | Ref: 3360.95 g | 36 | Ref: 3333.93 g | 0.361 |
SGA+ | |||||
Cotinine ng·mL−1 | |||||
<4 | 65 (7.9) | Ref: 1.00 | 3 (6.4) | Ref: 1.00 | |
4–20 | 44 (7.7) | 0.96 (0.67–1.39) | 8 (13.6) | 2.09 (0.58–7.49) | |
20–50 | 24 (11.1) | 1.25 (0.80–1.95) | 1 (5.6) | 0.85 (0.10–7.07) | |
>50 | 69 (15.9) | 1.83 (1.32–2.55) | 4 (11.1) | 1.73 (0.40–7.43) | 0.359 |
SHS exposure | |||||
No | 56 (7.8) | 0.76 (0.52–1.12) | 4 (8.0) | 1.24 (0.25–6.26) | |
Only outside the home | 32 (6.5) | 0.62 (0.40–0.97) | 6 (15.8) | 4.48 (1.10–18.18) | |
Inside the home | 44 (11.4) | Ref: 1.00 | 2 (5.6) | Ref: 1.00 | 0.099 |
Data are presented as n and coefficient (95% CI) for birth weight, and n (%) and relative risk (95% CI) for SGA, unless otherwise stated. Ref: reference. #: adjusted for sex (ref: male) and gestational age (centred to 40 weeks), maternal asthma, education (ref: university), social class (ref: non-manual), parity (ref: nulliparous), and height, weight and age (all centred to mean). ¶: if cotinine <50 ng·mL−1 or not reporting active smoking. +: adjusted for maternal education (ref: university), social class (ref: non-manual, only available for INMA cohort), parity (ref: nulliparous), and height, weight and age (all centred to mean).