Table 5– Predictors of treatments of primary ciliary dyskinesia (PCD) in European children: airway clearance therapy, inhaled corticosteroids, recombinant human deoxyribonuclease (rhDNase) and antibiotics
Airway clearance#Inhaled corticosteroids#rhDNaseAntibiotics for exacerbations#Prophylactic antibiotics#+
OR95% CIp-valueOR95% CIp-valueOR95% CIp-valueOR95% CIp-valueOR95% CIp-value
PCD patients cared for n
European region
 British Isles1.40.4––––3.32.501.0–6.3
  • Results are adjusted for size of centre (number of PCD children) and region. European regions are defined as follows. Western Europe: Austria, Belgium, France, Germany, the Netherlands and Switzerland (n=61); British Isles: Ireland and UK (n=33); southern Europe: Cyprus, Greece, Italy, Portugal and Spain (n=47); northern Europe: Denmark, Finland, Norway and Sweden (n=22); eastern Europe: Bulgaria, Czech Republic, Estonia, Hungary, Israel, Romania, Serbia, Slovakia and Turkey (n=31) (total n=194). OR: odds ratio; CI: confidence interval. #: routinely used (for all children); : frequently or sometimes used (for some children); +: prophylactic nebulised antibiotics, prophylactic oral antibiotics, intermittent oral antibiotics, regular intravenous antibiotics or intermittent intravenous antibiotics.