Serum selenium | ptrend§ | phetƒ | |||
Low# | Medium¶ | High+ | |||
Subjects n | 965 | 1141 | 1227 | ||
Smoking characteristics | |||||
Exposure pack-yrs | 32.4±28.4 | 28.5±24.0 | 24.5±23.4 | <0.001 | 0.94 |
Current smokers | 64.0 | 56.7 | 46.8 | <0.001 | <0.001 |
S-cotinine ng·mL−1 | |||||
<100 | 38.9 | 46.8 | 57.5 | ||
100–360 | 28.1 | 25.9 | 22.4 | <0.001 | <0.001 |
>360 | 33.0 | 27.3 | 20.1 | ||
Smokers in 1970–1971 | 74.9 | 68.6 | 63.4 | <0.001 | <0.001 |
Never-smokers | 8.2 | 11.3 | 13.3 | <0.001 | 0.001 |
Alcohol use | |||||
Alcoholic beverages per week | |||||
0 | 10.6 | 9.8 | 12.7 | ||
1–21 | 58.0 | 64.0 | 60.8 | 0.008 | 0.007 |
≥22 | 31.4 | 26.2 | 26.4 | ||
Beer drinkers | 78.7 | 74.8 | 69.8 | <0.001 | <0.001 |
Beer beverages per week | 12.9±11.3 | 10.5±8.3 | 10.5±8.7 | <0.001 | 0.003 |
Wine drinkers | 48.0 | 54.3 | 58.3 | <0.001 | <0.001 |
Wine beverages per week | 7.4±6.9 | 7.7±7.8 | 7.4±6.2 | 0.92 | 0.51 |
Spirits drinkers | 50.9 | 53.8 | 53.4 | 0.29 | 0.36 |
Spirits beverages per week | 7.1±6.1 | 6.1±4.9 | 5.9±4.9 | <0.001 | 0.14 |
Dietary factors | |||||
Salt## | 16.0 | 13.0 | 9.1 | <0.001 | <0.001 |
Fat¶¶ | 57.3 | 51.2 | 47.6 | <0.001 | <0.001 |
Occupational exposure | |||||
Long-term dust exposure++ | 6.9 | 7.1 | 8.5 | 0.16 | 0.30 |
Other characteristics | |||||
Chronic bronchitis | 19.9 | 13.7 | 10.7 | <0.001 | <0.001 |
Peak flow L·min−1 | 481±104 | 509±97 | 516±92 | <0.001 | 0.006 |
Low social class§§ | 60.2 | 50.9 | 46.5 | <0.001 | <0.001 |
Age yrs | 63.5±5.3 | 62.6±5.1 | 62.7±5.1 | 0.001 | 0.007 |
Data are presented as mean±sd or %, unless otherwise stated. ptrend: p-value for trend; phet: p-value for heterogeneity. #: 0.4–1.0 μmol·L−1; ¶: 1.1–1.2 μmol·L−1; +: 1.3–3.0 μmol·L−1; §: Kendall’s tau B or test for linearity in ANOVA; ƒ: Chi-squared test (likelihood ratio) or test for deviation from linearity in ANOVA; ##: uses more than others; ¶¶: does not avoid fatty foods; ++: ≥5 yrs; §§: class IV–V.