Table 3– Most commonly isolated pathogens at baseline and bacteriological eradication rates at end of therapy
Bacteriological eradication95% CI#
MoxifloxacinAmoxicillin/clavulanic acid
Population
 Per protocol with pathogens183/260 (70.4)168/261 (64.4)-0.7–15.2+
 Intent-to-treat with pathogens216/327 (66.0)197/335 (58.8)1.1–15.7§
Pathogen
Haemophilus influenzae58/65 (89.2)50/75 (66.7)8.1–37.1
Pseudomonas aeruginosa31/57 (54.5)32/54 (59.3)-25.1–15.3
Streptococcus pneumoniae44/49 (89.8)33/38 (86.8)-13.1–19.0
Klebsiella pneumoniae21/36 (58.3)19/48 (39.6)-4.9–42.4
Moraxella catarrhalis30/36 (83.3)37/43 (86.0)-21.2–15.8
Staphylococcus aureus20/23 (87.0)16/20 (75.0)-20.0–33.9
Escherichia coli14/21 (66.7)11/16 (68.8)-38.0–33.8
Serratia marcescens10/14 (71.4)9/14 (62.3)34.5–48.8
Enterobacter cloacae9/11 (81.8)7/8 (87.5)-48.8–37.4
Enterobacter aerogenes5/8 (62.5)6/8 (75.0)-70.0–45.0
Klebsiella oxytoca9/11 (81.8)2/4 (50.0)-39.3–100
Proteus mirabilis1/4 (25.0)6/9 (66.7)-100–28.8
  • Data are presented as bacteriological eradication+presumed eradication/total number of patients or organisms (%), unless otherwise stated. #: 95% confidence intervals for differences in organism eradication rates were generated using a normal approximation to the binomial distribution, with a continuity correction; : intent-to-treat with pathogen population; +: p=0.078; §:p=0.026.