Table 1– Patient characteristics
CharacteristicsGroup 1: IF positiveGroup 2: IF negative
Age yrs58.92 (17–83)±15.8956.68 (15–82)±13.55
Male/female45/26 (63.4)109/62 (63.7)
Immunocompromised71 (100)136 (79.5)
Autoimmune disease#18 (25.3)53 (31.0)
 Rheumatoid arthritis417
 Giant cell arteritis60
 ANCA-positive vasculitis42
 Systemic sclerosis09
 Granulomatosis with polyangiitis06
Solid organ transplantation#28 (39.4)37 (21.6)
 >1 organ11
Active haemato-oncological disease#23 (32.4)41 (24.0)
 Solid tumour36
 Acute myeloid leukaemia19
 Acute lymphoblastic leukaemia12
 Chronic lymphatic leukaemia34
 Hodgkin’s lymphoma32
 Non-Hodgkin’s lymphoma1214
 Multiple myeloma29
 Other haematological disease09
Other cause of immunosuppression#2 (2.8)5 (2.9)
Death18 (25.4)16 (9.34)
Pneumocystis diagnosis
 Definitive PCP (positive IF testing)71 (100)0 (0)
PCR Pneumocystis jirovecii results
 Positive qualitative PCR71 (100)18 (10.5)
 Quantitative PCR (log10) in case of positivity median (range)3.8 (1.94–6.17)2.18 (1.15–4.72)
  • Data are presented as n, median (range)±sd, n (%), unless otherwise stated. IF: immunofluorescence; ANCA: antineutrophil cytoplasmic antibody; PCP: Pneumocystitis pneumonia. #: the most relevant immunosuppression is chosen. For the specified diagnoses, more than one diagnosis per patient is possible.