Table 3– Unadjusted, partly adjusted and fully adjusted hazard ratio (HR) values for new nonfatal cardiovascular events in ischaemic stroke patients using Cox adjusted proportional regression

	Unadjusted model		Partly adjusted model^#		Fully adjusted model^¶
	HR (95% CI)	p-value	HR (95% CI)	p-value	HR (95% CI)	p-value
Atrial fibrillation	2.42 (1.25–4.67)	0.008	2.07 (1.08–3.76)	0.027	2.03 (1.09–3.8)	0.026
Barthel index	0.99 (0.98–0.99)	0.013	0.99 (0.98–0.99)	0.011	0.99 (0.98–1)	0.025
Previous stroke or TIA	1.94 (1.01–3.7)	0.046			2.01 (1.09–3.66)	0.024
AHI <10 events·h⁻¹	0.89 (0.25–3.17)	0.86	0.92 (0.28–3.02)	0.88	0.98 (0.3–3.21)	0.97
AHI 10-19 events·h⁻¹	0.95 (0.28–3.26)	0.93	0.98 (0.31–3.1)	0.98	1.05 (0.33–3.34)	0.93
AHI ≥20 events·h⁻¹ nontolerant CPAP	2.99 (1.14–7.93)	0.021	2.92 (1.09–7.56)	0.03	2.87 (1.11–7.71)	0.033
AHI ≥20 events·h⁻¹ with CPAP	0.66 (0.23–1.83)	0.42	0.69 (0.32–2.15)	0.64	0.78 (0.63–2.43)	0.51

TIA: transient ischaemic attack; AHI: apnoea/hypopnoea index; CPAP: continuous positive airway pressure. ^#: fully adjusted model minus adjustment by arterial hypertension, previous stroke or TIA and previous ischaemic heart disease.^¶: adjusted by age, sex, Barthel index, AHI and CPAP treatment groups, previous stroke or TIA; diabetes, lipid disorders, body mass index, current smoking, arterial hypertension, atrial fibrillation, significant carotid stenosis and fibrinogen levels.