Table 5– Baseline characteristics for group 3: pulmonary hypertension due to lung disease and/or hypoxia
IPAHCOPDILDSleep disorders and alveolar hypoventilation
Subjects n1751013225
Age yrs55±16#,¶69±10§68±11§61±10
Female67#,¶,+37§22§44§
WHO III/IV67/2067/25+53/44+,§67/8#,¶
ISWD m183±173#,¶102±105§97±97§145±99
ra mmHg11±610±58±711±7
pa mmHg53±13#,¶,+43±11§39±9§37±10§
CI L·min−1·m−22.3±0.8#,+2.8±0.9§2.5±0.6+3.2±0.7¶,§
Ppcw mmHg10±3#,+13±5+,§11±8+16±10#,¶,§
PVR dyn·s·cm−5960±465#,¶,+568±382§560±321§375±284§
Sv,O2 %61±9#,+64±8§63±1069±8§
FEV1 % pred86±15#,¶,+59±26§66±25§51±23§
FVC % pred97±18#,¶,+85±25¶,+,§66±25#,§56±23#,§
TL,CO % pred52±21#,¶32±16+,§32±9+,§57±19#,¶
  • Data are presented as mean±sd or %, unless otherwise stated. Idiopathic pulmonary arterial hypertension (IPAH) data are shown for comparison. COPD: chronic obstructive pulmonary disease; ILD: interstitial lung disease; WHO: World Health Organization functional class; ISWD: incremental shuttle walking distance; ra: mean right atrial pressure; pa: mean pulmonary artery pressure; CI: cardiac index; Ppcw: pulmonary capillary wedge pressure; PVR: pulmonary vascular resistance; Sv,O2: mixed venous oxygen saturation; FEV1: forced expiratory volume in 1 s; % pred: % predicted; FVC: forced vital capacity; TL,CO: transfer factor of the lung for carbon monoxide. #: p<0.05 in comparison to COPD; : p<0.05 in comparison to ILD; +: p<0.05 in comparison to sleep/alveolar hypoventilation; §: p<0.05 in comparison to IPAH.