Table 1– Characteristics of sarcoidosis patients
Löfgren’s syndromeNon-Löfgren’s
Patients n1310
Males/females n9/48/2
Age yrs median (range)37 (29–56)48 (33–67)*
Current smokers/ex-smokers/never-smokers n3/2/81/4/5
Radiographic stage 0/I/II/III/IV n0/10/3/0/00/2/3/2/3
BAL analyses
 Recovery % of instilled volume67 (60–72)59 (55–68)
 Viability %94 (93–96)95 (93–98)
 Total cell concentration ×106 cells·L−1172 (99–248)160 (125–191)
 Total cell number ×106 cells26 (13–38)23 (16–32)
 Differential cell counts
  Macrophages %77 (68–85)76 (64–86)
  Macrophages ×106 cells·L−1128 (81–174)124 (90–154)
  Lymphocytes %23 (13–30)22 (13–34)
  Lymphocytes ×106 cells·L−133 (13–66)27 (14–67)
  Neutrophils %1.0 (0.4–1.7)1.6 (0.4–2.3)
  Neutrophils ×106 cells·L−11.3 (0.9–2.9)2.5 (0.4–3.3)
  Eosinophils %0.2 (0–0.4)0.4 (0.2–0.8)
  Eosinophils ×106 cells·L−10.3 (0–0.5)0.6 (0.2–1.3)
  CD4+/CD8+ T-cell ratio5.0 (2.5–11)4.5 (3.5–9.0)
  AV2S3+ T-cells % of CD4+ T-cells28 (22–37)3.5 (2.5–6.7)***
Blood AV2S3+ T-cells % of CD4+ T-cells4.4 (3.9–5.2)ND
Pulmonary function tests
 VC % pred96 (86–104)90 (78–99)
 FEV1 % pred93 (76–102)90 (75–101)
DL,CO % pred94 (91–107)#82 (24–83)
  • Data are presented as median (interquartile range), unless otherwise stated. BAL: bronchoalveolar lavage; VC: vital capacity; % pred: % predicted; FEV1: forced expiratory volume in 1 s; DL,CO: diffusing capacity of the lung for carbon monoxide; ND: not determined. #: n=12; : n=3. *: p<0.05 by Mann–Whitney U-test; ***: p<0.001 by Mann–Whitney U-test.