Table 2– Progressive metabolic impairment is associated with increasing obstructive sleep apnoea severity but not with increasing excessive daytime sleepiness
Number of metabolic syndrome componentsRho/tau
012345
Subjects n55811211349444
Age yrs40.9±13.146.6±12.052.5±12.552.9±11.854.3±11.555.9±13.40.305***
Diabetes mellitus001020.536.447.70.338***
BMI kg·m−224.5±2.728.2±4.629.7±5.232.5±5.534.2±6.134.4±5.60.548***
Obesity#3.728.048.668.68184.60.517***
Neck circumference cm37.5±3.239.6±3.741.1±3.342.3±3.744.2±4.143.8±4.00.462***
AHI events·h−122.9±17.631.5±20.836.8±23.549.9±26.856.2±28.161.9±31.20.428***
ArI events·h−134.3±16.941.6±17.046.1±20.756.2±22.664.2±23.565.0±22.40.428***
Mean nocturnal Sa,O2 %95.3±2.094.1±2.393.2±2.891.5±4.190.2±4.690.2±4.9-0.466***
Lowest Sa,O2 %87.1±5.784.6±6.783.1±7.278.2±9.477.6±9.874.3±11.5-0.419***
ESS score9.9±5.29.7±5.39.0±4.99.7±5.110.5±4.99.7±5.60.036
Systolic blood pressure mmHg113.3±8.5121.7±13.7130.3±16.9135.0±15.2139.3±17.7144.1±10.50.522***
Diastolic blood pressure mmHg68.0±9.074.6±9.479.6±11.582.6±12.385.2±11.286.8±10.70.429***
Waist circumference cm88.9±9.399.8±11.5105.3±11.1112.4±12.0115.4±13.1114.8±11.50.575***
HDL cholesterol mg·dL−160.1±13.657.1±14.957.4±22.751.3±10.649.8±22.341.6±11.7-0.363***
Triglycerides mg·dL−185.6±31.4113.3±58.0129.8±54.2160.0±74.3205.5±94.8245.8±132.10.598***
Fasting blood glucose mg·dL−188.5±6.691.8±6.5101.8±26.1110.1±24.7117.7±27.5128.7±30.00.614***
  • Data are presented as mean±sd or %, unless otherwise stated. BMI: body mass index; AHI: apnoea/hypopnoea index; ArI: arousal index; Sa,O2: arterial oxygen saturation; ESS: Epworth Sleepiness Scale; HDL: high-density lipoprotein. #: BMI ≥30 kg·m−2. ***: p<0.001 for trend.