Table 4– Adjusted risk ratios# for infections and current asthma (n=27) at 10 yrs in relation to age of sensitisation
CharacteristicAtopic by 2 yrsp-valueAtopic after 2 yrsp-value
Subjects n6922
Whole population regardless of ARI history2.09 (0.99–4.43)0.0551.52 (0.68–3.40)0.306
Infections in first year
 Any febrile infections2.28 (1.16–4.46)0.0171.91 (0.75–4.85)0.176
 Any febrile URI1.22 (0.54–2.72)0.6332.01 (0.82–4.92)0.126
 Any LRI with fever4.92 (2.59–9.36)<0.0011.13 (0.19–6.79)0.895
 Any LRI without fever1.53 (0.77–3.07)0.2271.96 (0.81–4.71)0.134
 Any wheezy or febrile LRI2.92 (1.45–5.88)0.0030.61 (0.09–3.97)0.601
 Any wheezy LRI1.41 (0.60–3.33)0.4291.50 (0.42–5.30)0.530
 Any wheezy LRI with fever2.30 (0.98–5.43)0.0572.33 (0.41–13.07)0.338
 Any wheezy LRI without fever1.61 (0.70–3.71)0.2661.12 (0.19–6.55)0.903
 Any wheezy LRI associated with HRV or RSV1.36 (0.54–3.43)0.5192.24 (0.75–6.64)0.146
 Any wheezy LRI associated with HRV1.36 (0.54–3.43)0.5193.36 (1.13–9.99)0.029
 Any wheezy LRI associated with RSV1.47 (0.25–8.61)0.6680
  • Data are presented as risk ratio (95% CI), unless otherwise stated. ARI: acute respiratory illnesses; URI: upper respiratory illness; LRI: lower respiratory illness; HRV: human rhinoviruses; RSV: respiratory syncytial virus. #: adjusted for sex, breastfeeding, pet ownership, older siblings, second-hand tobacco smoke exposure and daycare attendance. Bold indicates statistical significance.