Table 2– Clinical outcomes at 6 and 12 months in endobronchial valve (EBV)-treated and control patients stratified by computed tomography fissure integrity
Complete fissureIncomplete fissure
EBVControl#p-valueEBVControlp-value
Patients n44196740
Δ FEV1 %
 6 months16±212±140.021±18-1±210.7
 12 months15±29-2±220.040±23-2±190.6
Δ 6MWD %
 6 months11±3419±540.67 ±362±190.4
 12 months13±3510±440.85±300 ±340.5
Δ cycle workload W
 6 months4±14-3±70.030±14-3±110.4
 12 months4±14-2±90.10-2±13-6±130.2
Δ SGRQ points
 6 months-6±153±150.09-4±14-1±140.2
 12 months0±154±110.4-1±14-1±140.9
Lost to follow-up7 (16)06 (9)2 (5)
Died2 (5)1 (5)4 (6)3 (8)
  • Data are presented as mean±sd or n (%), unless otherwise stated. Δ: change; FEV1: forced expiratory volume in 1 s; 6MWD: 6-min walk distance; SGRQ: St George’s Respiratory Questionnaire. #: n=1 control missing fissure integrity data.