Treatment | Control | p-value | |
CT volumes and SGRQ responders# n | 8/33 | 0/35 | 0.002 |
CT lung volumes % change | |||
Upper lobes (treated) | -7.3±9 | 0.7±5.2 | <0.0001 |
Non-upper lobes (untreated) | 6.7±14.5 | 0.2±7.8 | 0.027 |
SGRQ total score | -4.3±16.2 | -3.6±10.7 | 0.837 |
Data are presented as mean±sd, unless otherwise stated. #: responder defined as having both a ≥4-point improvement in SGRQ and a volume decrease in upper lobes with a compensatory volume increase of ≥7.5% in non-treated lobes measured by CT (composite end-point).