Variable | Hazard ratio (95% CI) | p-value |
Prospective cohort# | ||
MRC dyspnoea score >3 | 6.77 (2.37–19.41) | 0.0005 |
6MWD <72% pred | 3.27 (1.25–8.82) | 0.0162 |
CPI >41 | 5.36 (1.50–34.15) | 0.0071 |
Retrospective cohort¶ | ||
6MWD <72% pred | 5.43 (1.35–36.17) | 0.016 |
CPI >41 | 4.20 (1.05–27.93) | 0.042 |
MRC: Medical Research Council; 6MWD: 6-min walking distance; % pred: % predicted; CPI: composite physiologic index. #: p-value of the model <0.0001; ¶: p-value of the model 0.0053.