RT Journal Article SR Electronic T1 Towards tuberculosis elimination: an action framework for low-incidence countries JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP 928 OP 952 DO 10.1183/09031936.00214014 VO 45 IS 4 A1 Knut Lönnroth A1 Giovanni Battista Migliori A1 Ibrahim Abubakar A1 Lia D'Ambrosio A1 Gerard de Vries A1 Roland Diel A1 Paul Douglas A1 Dennis Falzon A1 Marc-Andre Gaudreau A1 Delia Goletti A1 Edilberto R. González Ochoa A1 Philip LoBue A1 Alberto Matteelli A1 Howard Njoo A1 Ivan Solovic A1 Alistair Story A1 Tamara Tayeb A1 Marieke J. van der Werf A1 Diana Weil A1 Jean-Pierre Zellweger A1 Mohamed Abdel Aziz A1 Mohamed R.M. Al Lawati A1 Stefano Aliberti A1 Wouter Arrazola de Oñate A1 Draurio Barreira A1 Vineet Bhatia A1 Francesco Blasi A1 Amy Bloom A1 Judith Bruchfeld A1 Francesco Castelli A1 Rosella Centis A1 Daniel Chemtob A1 Daniela M. Cirillo A1 Alberto Colorado A1 Andrei Dadu A1 Ulf R. Dahle A1 Laura De Paoli A1 Hannah M. Dias A1 Raquel Duarte A1 Lanfranco Fattorini A1 Mina Gaga A1 Haileyesus Getahun A1 Philippe Glaziou A1 Lasha Goguadze A1 Mirtha del Granado A1 Walter Haas A1 Asko Järvinen A1 Geun-Yong Kwon A1 Davide Mosca A1 Payam Nahid A1 Nobuyuki Nishikiori A1 Isabel Noguer A1 Joan O'Donnell A1 Analita Pace-Asciak A1 Maria G. Pompa A1 Gilda G. Popescu A1 Carlos Robalo Cordeiro A1 Karin Rønning A1 Morten Ruhwald A1 Jean-Paul Sculier A1 Aleksandar Simunović A1 Alison Smith-Palmer A1 Giovanni Sotgiu A1 Giorgia Sulis A1 Carlos A. Torres-Duque A1 Kazunori Umeki A1 Mukund Uplekar A1 Catharina van Weezenbeek A1 Tuula Vasankari A1 Robert J. Vitillo A1 Constantia Voniatis A1 Maryse Wanlin A1 Mario C. Raviglione YR 2015 UL http://erj.ersjournals.com/content/45/4/928.abstract AB This paper describes an action framework for countries with low tuberculosis (TB) incidence (<100 TB cases per million population) that are striving for TB elimination. The framework sets out priority interventions required for these countries to progress first towards “pre-elimination” (<10 cases per million) and eventually the elimination of TB as a public health problem (less than one case per million). TB epidemiology in most low-incidence countries is characterised by a low rate of transmission in the general population, occasional outbreaks, a majority of TB cases generated from progression of latent TB infection (LTBI) rather than local transmission, concentration to certain vulnerable and hard-to-reach risk groups, and challenges posed by cross-border migration. Common health system challenges are that political commitment, funding, clinical expertise and general awareness of TB diminishes as TB incidence falls. The framework presents a tailored response to these challenges, grouped into eight priority action areas: 1) ensure political commitment, funding and stewardship for planning and essential services; 2) address the most vulnerable and hard-to-reach groups; 3) address special needs of migrants and cross-border issues; 4) undertake screening for active TB and LTBI in TB contacts and selected high-risk groups, and provide appropriate treatment; 5) optimise the prevention and care of drug-resistant TB; 6) ensure continued surveillance, programme monitoring and evaluation and case-based data management; 7) invest in research and new tools; and 8) support global TB prevention, care and control. The overall approach needs to be multisectorial, focusing on equitable access to high-quality diagnosis and care, and on addressing the social determinants of TB. Because of increasing globalisation and population mobility, the response needs to have both national and global dimensions.Action framework for countries with low tuberculosis incidence: a coherent approach for eliminating tuberculosis http://ow.ly/H03ZZ