RT Journal Article SR Electronic T1 Radial endobronchial ultrasound images for ground-glass opacity pulmonary lesions JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP 1661 OP 1668 DO 10.1183/09031936.00167914 VO 45 IS 6 A1 Takehiro Izumo A1 Shinji Sasada A1 Christine Chavez A1 Yuji Matsumoto A1 Takaaki Tsuchida YR 2015 UL http://erj.ersjournals.com/content/45/6/1661.abstract AB Radial endobronchial ultrasound (R-EBUS) is a useful tool for precise localisation of peripheral pulmonary lesions, but there have been no detailed reports about the use of R-EBUS images for ground-glass opacity (GGO). The R-EBUS images of 116 patients with GGO, who were diagnosed as having adenocarcinoma by R-EBUS with a guide sheath (EBUS-GS), were compared with the respective chest computed tomography findings. In 103 patients, R-EBUS images were correlated with the histological surgical specimens. R-EBUS images of GGO were identified based on the internal structure of the lesion and classified into two groups. Blizzard showed an enlarged, diffuse hyperintense acoustic shadow. Mixed blizzard showed a combination of blizzard and some diffuse heterogeneity with several hyperechoic dots and vessels. All pure GGO lesions (nine out of nine) were blizzard on R-EBUS. For part-solid GGOs, the percentage of mixed blizzard was inversely related to the amount of the GGO component. Histological findings from surgery revealed that all blizzard lesions were on the spectrum of adenocarcinoma in situ to well differentiated adenocarcinoma while majority (33 out of 64) of mixed blizzard lesions were moderately to poorly differentiated adenocarcinoma. R-EBUS types are important to locate GGOs prior to transbronchial sampling with EBUS-GS. The classification of R-EBUS images is useful to decide the location of GGOs during transbronchial biopsy with R-EBUS http://ow.ly/FmCBR