RT Journal Article
SR Electronic
T1 Analysis of advanced lung cancer patients diagnosed following emergency admission
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP 1098
OP 1107
DO 10.1183/09031936.00068114
VO 45
IS 4
A1 Daichi Fujimoto
A1 Ryoko Shimizu
A1 Takeshi Morimoto
A1 Ryoji Kato
A1 Yuki Sato
A1 Mariko Kogo
A1 Jiro Ito
A1 Shunsuke Teraoka
A1 Takehiro Otoshi
A1 Kazuma Nagata
A1 Atsushi Nakagawa
A1 Kojiro Otsuka
A1 Nobuyuki Katakami
A1 Keisuke Tomii
YR 2015
UL http://erj.ersjournals.com/content/45/4/1098.abstract
AB Data on prognosis and predictors of overall survival in advanced lung cancer patients diagnosed following emergency admission (DFEA) are currently lacking.We retrospectively analysed data from 771 patients with advanced nonsmall cell lung cancer between April 2004 and April 2012.Of the 771 patients, 103 (13%) were DFEA. DFEA was not an independent predictor of overall survival by multivariate Cox proportional hazard models, whereas good performance status (PS), epidermal growth factor receptor gene mutation, stage IIIB, adenocarcinoma and chemotherapy were independent predictors of overall survival (hazard ratio (95% CI) 0.36 (0.29–0.44), p<0.001; 0.49 (0.38–0.63), p<0.001; 0.64 (0.51–0.80), p<0.001; 0.81 (0.67–0.99), p=0.044; and 0.40 (0.31–0.52), p<0.001, respectively). Good PS just prior to opting for chemotherapy, but not at emergency admission, was a good independent predictor of overall survival in DFEA patients (hazard ratio (95% CI) 0.26 (0.12–0.55); p<0.001).DFEA is relatively common. DFEA and PS at emergency admission were not independent predictors of overall survival, but good PS just prior to opting for chemotherapy was an independent predictor of longer overall survival. Efforts to improve patient PS after admission should be considered vital in such circumstances.Efforts to improve performance status after admission are vital in patients diagnosed following emergency admission http://ow.ly/C3BDQ