@article {SterlikovP2635, author = {Sergey Sterlikov and Vadim Testov}, title = {The risk of default in TB patients in the Russian Federation}, volume = {44}, number = {Suppl 58}, elocation-id = {P2635}, year = {2014}, publisher = {European Respiratory Society}, abstract = {The risk of default in MDR-TB and non MDR-TB cohorts for new cases and previously treated patients was estimated.Methods. A prospective cohort review of patients treated in 2010 included: 1). 3.760 MDR-TB cases including 995 new TB cases, 534 relapses and 2231 other retreatment cases (1.297-after treatment failure, 161-after default and 773 {\textendash} from group {\textquotedblleft}other{\textquotedblright}); 2). 10.458 non MDR-TB patient including 7717 new cases, 1149 relapses and 1592 other retreatment cases). Absolute (AR) and relative risk (RR) of default were calculated.View this table:Risk of defaultResults. Treatment success and default rates comprised for: new MDR-TB cases {\textendash} 60.7\% and 15.4\%; new non MDR-TB cases - 67.2\% and 12.7\%; MDR-TB relapses {\textendash} 51.9\% and 14.0\%; non MDR-TB relapses {\textendash} 54.0\% and 12.4\%; other MDR-TB retreatments {\textendash} 39.2\% and 21.4\%; other non MDR-TB retreatments {\textendash} 34.8\% and 22.0\% respectively. New MDR-TB cases demonstrated maximal RR of default due to increasing of treatment duration. There were not significant differences in the RR for MDR-TB and non MDR-TB patients with relapses and other retreatment cases. MDR-TB patients from group {\textquotedblleft}treatment after default{\textquotedblright} demonstrated maximal AR of default and 30\% of them resulted as defaulters.Conclusion. New MDR-TB patients have maximal RR of default but highest treatment success rate and they are focus group for default prevention tools.}, issn = {0903-1936}, URL = {https://erj.ersjournals.com/content/44/Suppl_58/P2635}, eprint = {https://erj.ersjournals.com/content}, journal = {European Respiratory Journal} }