PT - JOURNAL ARTICLE AU - Martin Edwards AU - Sarah Kotecha AU - John Lowe AU - W. John Watkins AU - A. John Henderson AU - Sailesh Kotecha TI - Respiratory and neurological outcomes in children born preterm study (RANOPs): Early Term outcomes DP - 2014 Sep 01 TA - European Respiratory Journal PG - P1252 VI - 44 IP - Suppl 58 4099 - http://erj.ersjournals.com/content/44/Suppl_58/P1252.short 4100 - http://erj.ersjournals.com/content/44/Suppl_58/P1252.full SO - Eur Respir J2014 Sep 01; 44 AB - IntroductionEarly term deliveries, which are common in mothers who have elective Caesarean section, are at increased risk of respiratory and other health related problems in the neonatal period compared to full term born children.AimsTo assess if early term (37-38 weeks) born infants had greater respiratory symptoms in childhood compared to term (≥39 weeks) born children.MethodsA cross sectional survey of preterm-born children in Wales with matched term-control (N=13361) children was undertaken. Children aged 1-10 years old were sent questionnaires (based on ISAAC) to assess respiratory and general health outcomes with additional data gathered from national health database. Data was analysed for the term controls (early term vs full term) and children <5 or ≥ 5 years of age.Results548 early term born children and 2313 term born children were included. Early term-born children had higher rates of admission on the neonatal unit and admission during their first year of life (OR 1.6, p<0.001). 41% of early term born children report 'ever wheezing' vs 33% term born children (OR 1.4, p<0.001) and 15% vs 9.5% report having been diagnosed with a breathing problem such as asthma or recurrent wheeze (OR 1.7, p<0.001). Children <5 years old, born early term reported more wheezing during the day time over the last 3 months than term controls (OR 1.7, p=0.001). Early term-born children aged 5-10 years reported more wheezing episodes over the last 12 months than term controls (OR 1.5, p=0.034).ConclusionEarly term born children had significantly increased respiratory symptoms when compared to term-born children at both time periods of <5 & ≥5 years of age.