RT Journal Article SR Electronic T1 Acute myocardial infarction among Spanish adults with and without COPD: Cumulative incidence and outcomes JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP P4729 VO 44 IS Suppl 58 A1 Javier de Miguel Díez A1 Rodrigo Jiménez García A1 Alicia Oliva Ramos A1 Valentín Hernández Barrera A1 Ana López de Andrés A1 Milagros Llanos Flores A1 Irene Jarana Aparicio A1 Julio Cesar Vargas Espinal A1 Luis Puente Maestu A1 Pilar Carrasco Garrido YR 2014 UL http://erj.ersjournals.com/content/44/Suppl_58/P4729.abstract AB Background: This study aims to describe trends in the rate of acute myocardial infarction (AMI) in patients with and without COPD in Spain, 2001-2010.Methods: We selected all patients with a discharge of AMI using national hospital discharge data. Discharges were grouped by COPD status: COPD and non COPD. The cumulative incidence of discharges attributed to AMI were calculated overall and stratified by COPD status and year. We calculated length of stay (LOS) and in-hospital mortality (IHM).Results: From 2001 to 2010, 513,517 discharges with AMI were identified (7.79% with COPD). The cumulative incidence of discharges due to AMI in COPD patients increased (from 15.69 cases per 100,000 in 2001 to 18.4 in 2003), then decreased to 12.77% in 2010. The pattern was similar in non-COPD patients. It increased from 193.22 cases per 100.000 in 2001 to 211.12 in 2010, and then decreased to 177.79 in 2010. LOS and IHM decreased significantly over time in both groups. LOS decreased from 10.71 (9.64) days in 2001 to 9.09 (9.21) days in 2010 in COPD patients, and from 9.97 (9.14) days in 2001 to 8.9 (9) days in 2010 in non-COPD patients. IHM also decreased from 12.29% in 2001 to 10.82% in 2010 in COPD patients, and from 11.67% to 8.17% in 2010 in non-COPD patients.Conclusions: AMI hospitalization rates increased initially and have since declined slowly. LOS and IHM have decreased significantly in both groups, remaining higher in COPD patients.