RT Journal Article SR Electronic T1 Correlation of clinical, laboratory and functional parameters in stable chronic obstructive pulmonary disease JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP P2192 VO 44 IS Suppl 58 A1 Unlu, Mehmet A1 Cimen, Pinar A1 Kirakli, Cenk A1 Katgi, Nuran A1 Varol, Yelda A1 Kayaalp, Ismail A1 Ayranci, Aysu A1 Guclu, Salih Zeki YR 2014 UL http://erj.ersjournals.com/content/44/Suppl_58/P2192.abstract AB Dyspnea is most important symptom affecting the daily lives of COPD patients.It is not possible to determine the degree of dyspnea and quality of life only by spirometry.Additional markers are needed to assess the perception of dyspnea and the quality of life.In addition anxiety and depression are the most common comorbidities affecting the lives of patients with COPD.In this study we evaluated perception and degree of dyspnea in stable COPD patients with different measurement methods and investigate the correlation between the clinical,laboratory and functional parameters with dyspnea scales;and also aimed to determine relationship between level of COPD and psychological influence of the COPD patients.101 COPD patients that were admitted to hospital were included to the study between June 2012-December 2012.OCD and BDI dyspnea scales that were used to assess patients, showed a strong positive correlation with FEV1(p<0.05).Also VAS,MBS and mMRC had a significant positive correlation with FEV1(p<0.001).SGRQ's subunits,respiratory questionnaire assessing quality of life,SGRQsymptom,SGRQactivity had a strong negative correlation with FEV1 (p<0.001),and FEV1 had a very strong negative correlation with SGRQtotal(p<0,05).Also HAD questionnaire had strong negative relationship with OTD and BDI dyspnea scales (p<0.001),and showed a positive relationship with mMRC and MBS scores (p<0.001).Both anxiety and depression had a strong positive correlation with SGRQ scores (p<0.001).In conclusion,FEV1 is not enough for evaluation of COPD.Dyspnea and the quality of life scales are needed.Also clinicians should be alert in terms of anxiety and depression in COPD.