PT  - JOURNAL ARTICLE
AU  - de Mir, Ines
AU  - Sardon, Olaia
AU  - Corcuera, Paula
AU  - Sanchez Solis, Manuel
AU  - Caballero, Araceli
AU  - Perez, Virginia
AU  - Hoo, A.F.
AU  - Stocks, Janet
AU  - Gonzalez Perez-Yarza, Eduardo
AU  - Moreno-Galdó, Antonio
TI  - Impaired lung function in 'healthy' preterm infants: Interpretation using new equipment-specific reference equations
DP  - 2014 Sep 01
TA  - European Respiratory Journal
PG  - P1151
VI  - 44
IP  - Suppl 58
4099  - https://publications.ersnet.org//content/44/Suppl_58/P1151.short
4100  - https://publications.ersnet.org//content/44/Suppl_58/P1151.full
SO  - Eur Respir J2014 Sep 01; 44
AB  - Even in the absence of overt respiratory disease during the neonatal period, reduced lung function has been reported in preterm infants. Meaningful interpretation of such results is, however, dependent on availability of appropriate controls and/or reference equations.Objectives. To assess the applicability of equipment-specific reference equations in healthy Spanish White fullterm infants, and the impact of preterm delivery on lung function during the first year of life.Methods. Lung function was measured under chloral sedation in clinically stable and asymptomatic 'healthy' preterm (30-35.8 w) and fullterm babies, using the CareFusionTM Masterscreen BabyBody equipment according to ERS/ATS guidelines. Data were expressed as z-scores to adjust for sex, age and body size (Lum, Ped Pulm 2010; Nguyen, Ped Pulm 2013;).Results. 79 term and 77 preterm infants were studied at mean (SD) corrected postnatal age of 5.92 (0.8) months (term) and 5.95 (1.01) months (preterm). No differences were found either in tidal breathing parameters or Rrs.View this table:Conclusions. Mean z-scores for term infants were all within 0.3 z-scores of the predicted published norms, suggesting that these equations are appropriate for Spanish infants Compared to term controls, 'healthy' preterm infants had significantly lower V'maxFRC, FEV0.5 and FEF25-75.