RT Journal Article SR Electronic T1 Osteoporosis in lung transplant patients JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP P2456 VO 44 IS Suppl 58 A1 Víctor Manuel Mora Cuesta A1 David Iturbe Fernandez A1 Elena Gallardo Agromayor A1 Luis Cerezal Pesquera A1 Cristina Ciorba A1 Amaya Martínez Meñaca A1 Jose Alberto Espinoza Pérez A1 Diego José Ferrer Pargada A1 Juan Jose Ruiz Cubillán A1 Jose Manuel Cifrián Martínez A1 Sonia Fernandez Rozas A1 Ramón Agüero Balbín A1 Felipe María Zurbano Goñi YR 2014 UL http://erj.ersjournals.com/content/44/Suppl_58/P2456.abstract AB Glucocorticoids are commonly used drugs in various lung diseases. Using them combined with low physical activity and other comorbidities result in a high percentage of osteoporosis in these patients. Some of these patients then end up having lung transplants, which are treated with high doses of corticoids . Here we present a retrospective analysis in which we study the prevalence of osteopenia and osteoporosis in patients who were treated with pulmonary transplant, measured by densitometry (gr/cm2 and T-score, at lumbar region, neck femur and total femur) and following the WHO criteria at different moments: pre-transplant and post-transplant (6, 12, 18, 24, 36, 48, 60 months). We have a total of 227 patients (34.80% women and 65.19% men). The age average was 53,86 years (± 10.84). Bilateral lung transplant (68.72%), unipulmonar transplant (30.39%), cardiopulmonar (0.44%). The results that we obtained were analysed by age, gender, treatment, base lung pathology and number of rejections in the first year. We observed a high prevalence of low bone mineral density pre-transplant (osteoporosis 48.48%, osteopenia 35.60%). After the transplant there was also a high osteoporosis and osteopenia prevalence in all groups (Osteoporosis+Osteopenia; 85.82%, 91.95%, 86.01%, 90.69%, 91.07%, 85.41%, 80.95% at 6, 12, 18, 24, 36, 48, 60 months respectively. Patients analysed at 5 years were younger than the others). There was a bigger percentage of women and older people who have osteoporosis and osteopenia. In conclusion most patients that need a pulmonary transplant already have a low bone mineral density, this condition remains and worsens most likely due to glucocorticoids as a primary treatment, low physical activity and comorbidities.