PT - JOURNAL ARTICLE AU - Silvia Montella AU - Eugenio Baraldi AU - Salvatore Cazzato AU - Raffaele Aralla AU - Mariangela Berardi AU - Luigia Maria Brunetti AU - Claudia Calogero AU - Anna Rita Cappiello AU - Fabio Cardinale AU - Maria Elisa di Cicco AU - Emanuela Di Palmo AU - Sabrina Di Pillo AU - Marzia Duse AU - Grazia Fenu AU - Giuliana Ferrante AU - Fabrizio Franceschini AU - Amelia Licari AU - Giuseppina Marrazzo AU - Maria Pia Natale AU - Maria Francesca Patria AU - Giorgio Piacentini AU - Vincenzo Ragazzo AU - Nicola Ullmann AU - Franca Rusconi TI - Severe asthma (SA) compared to non severe persistent asthma (PA) in children: An Italian on-line database DP - 2014 Sep 01 TA - European Respiratory Journal PG - P4245 VI - 44 IP - Suppl 58 4099 - http://erj.ersjournals.com/content/44/Suppl_58/P4245.short 4100 - http://erj.ersjournals.com/content/44/Suppl_58/P4245.full SO - Eur Respir J2014 Sep 01; 44 AB - SA has been described as a heterogeneous disease with regard to clinical presentation and course. Few data are available in children.We present data on 37 patients 6-17 years old with SA defined according to recent ERS/ATS Guidelines (Eur Respir J 2014) in comparison with 64 age-matched peers with PA controlled by medium-dose inhaled steroids followed at specialised centres adhering to the Italian Society for Paediatric Respiratory Diseases (SIMRI). Each centre filled in questionnaires (medical + parental questionnaires + patient questionnaire if >12 yrs) on the web (CINECA). Cases included in 2013 are shown.The table summarizes main demographic and clinical history characteristics, lung function and atopic findings, comorbidities/contributory factors, and personal/family impact of the disease.These preliminary findings confirm that children with SA are a heterogeneous group. Distinguishing characteristics are age at asthma diagnosis, food sensitisation, atopic dermatitis, total IgE and lung function. SA represents an important burden to personal and family life.