RT Journal Article SR Electronic T1 Clinical profile and survival of patients undergoing surgery for non-small cell lung cancer: Impact of positron emission tomography adoption JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP P2771 VO 44 IS Suppl 58 A1 Christelle Clément-Duchêne A1 Irawati Lemonnier A1 Francis Guillemin A1 Jean-Michel Vignaud A1 Guillaume Gauchotte A1 Stéphanie Lacomme A1 Gilles Grosdidier A1 Joëlle Siat A1 Yves Martinet YR 2014 UL http://erj.ersjournals.com/content/44/Suppl_58/P2771.abstract AB Background: According to staging, 20% of lung cancer patients can be cured with surgical treatment. This study will analyze the staging impact of [18F]Fluorodeoxyglucose Positron Emission Tomography (PET) on clinical characteristics, and survival in surgical non-small cell lung cancers (NSCLC).Aim and methods: Evaluation of the impact of PET adoption on survival of 1877 consecutive NSCLC patients treated with surgery, in Nancy, between 1988 and 2013. Two groups were established: G1=before PET introduction: 1998-2003/G2=after PET introduction: 2004-2013. Descriptive statistical analyses, and survival analysis were done according to the Kaplan-Meïer method.Results: Adenocarcinoma was the most frequent histological types in G2 (39.7% adenocarcinoma vs 22.8% squamous cell carcinoma, p<0.0001). The pourcentage of women increased ever time (G2: 22.6% vs G1: 13.8%, p<0.0001), as well as non-smokers pourcentage (7.1% vs 6.8%, p=0;0092),and early stages (IA) (29.7% vs 16.6%, p<0.0001). The combination of chemotherapy, radiation therapy, and surgery were the most common treatments in G2 vs G1 (13.6% vs 8.8%, p<0.0001), as post-surgical radiation therapy (15.4% vs 6.5%, p<0.0001). G2 patients vs G1in G2 had a better survival (p<0.0001). Women had a better survival for the whole cohort (p<0.0001), and in G1 (p<0.0001), but they did not have a better survival in G2 (p=0.137). Non-smokers had a better survival than smokers for the whole cohort, G1, and G2 (p=0.0009; p=0.0473 ; p=0.0033).Conclusions: The introduction of PET has an impact on the profile, and the survival of NSCLC treated with surgery.